Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.56 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848161 | 0.90 | MAOB (0.60) | LTB4RLTB4R2MAOBNR4A2SMPD1 | |
| SCHEMBL5801447 | 0.86 | ALOX5 (0.61) | LTB4RLTB4R2MAOBNR4A2FFAR1 | |
| SCHEMBL27424890 | 0.84 | CTBP2 (0.56) | SMN1; SMN2MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL12746034 | 0.82 | NR4A2 (0.58) | LTB4RLTB4R2MAOBNR4A2SMPD1 | |
| SCHEMBL10683288 | 0.82 | FFAR1 (0.63) | LTB4RLTB4R2MAOBNR4A2SMPD1 | |
| SCHEMBL670027 | 0.81 | MAOB (0.68) | LTB4RLTB4R2MAOBNR4A2SMPD1 | |
| SCHEMBL7531827 | 0.81 | PTPN1 (0.73) | MAOBNR4A2SMPD1PTPN1MEN1 | |
| SCHEMBL25452779 | 0.81 | MAOB (0.60) | LTB4RLTB4R2MAOBNR4A2SMPD1 | |
| SCHEMBL954459 | 0.81 | NR4A2 (0.66) | LTB4RLTB4R2MAOBNR4A2SMPD1 | |
| SCHEMBL2637708 | 0.80 | ALDH1A1 (0.57) | CYP4F2CYP4A11TSHRSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057505-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |