Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL392863 | 0.89 | ALOX5 (0.66) | ALOX5NPC1RAB9ASMN1; SMN2MAOB | |
| SCHEMBL2637708 | 0.86 | ALDH1A1 (0.57) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5800707 | 0.86 | LTB4R (0.56) | RAB9ASMN1; SMN2MAOBLTB4RLTB4R2 | |
| SCHEMBL11156485 | 0.86 | FFAR1 (0.67) | NPC1RAB9ASMN1; SMN2MAOBLTB4R | |
| SCHEMBL8037910 | 0.85 | ALOX5 (0.61) | ALOX5NPC1RAB9ASMN1; SMN2MAOB | |
| SCHEMBL9571882 | 0.84 | ALOX5 (0.62) | ALOX5NPC1RAB9ASMN1; SMN2MAOB | |
| SCHEMBL13905811 | 0.83 | ALOX5 (0.66) | ALOX5RAB9ASMN1; SMN2MAOBLTB4R | |
| SCHEMBL12688088 | 0.82 | NPC1 (0.70) | ALOX5NPC1RAB9ASMN1; SMN2MAOB | |
| SCHEMBL7236732 | 0.82 | FFAR1 (0.61) | ALOX5NPC1RAB9ASMN1; SMN2MAOB | |
| SCHEMBL16511748 | 0.82 | LTB4R (0.57) | ALOX5NPC1RAB9ASMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057505-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |