Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6716631 | 0.86 | GAA (0.33) | GAANPSR1 | |
| SCHEMBL323313 | 0.73 | GAA (0.60) | GAANPSR1 | |
| SCHEMBL1336591 | 0.70 | ALOX5 (0.46) | — | |
| SCHEMBL2028801 | 0.69 | — | — | |
| SCHEMBL3358107 | 0.68 | MAOA (0.36) | — | |
| SCHEMBL14893229 | 0.68 | — | — | |
| SCHEMBL28106332 | 0.68 | NOS3 (0.41) | — | |
| SCHEMBL7268014 | 0.68 | CA9 (0.39) | GAANPSR1 | |
| SCHEMBL15046597 | 0.68 | ALDH1A1 (0.50) | GAA | |
| SCHEMBL670334 | 0.67 | ALDH1A1 (0.49) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751893-B2 | Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS, INC. (US) | 2017-09-05 | — | — | US | disclosed |
| EP-1615890-A1 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION | WARNER-LAMBERT COMPANY (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004089903-A1 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-21 | — | — | WO | disclosed |