Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18148654 | 0.83 | CYP11B2 (0.39) | TP53SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL9261907 | 0.79 | SMN1; SMN2 (0.43) | TP53SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL20323533 | 0.79 | CYP11B1 (0.44) | SMN1; SMN2CYP11B2ALDH1A1GAAKMT2A | |
| SCHEMBL8970098 | 0.78 | CCR3 (0.37) | ALDH1A1GAADDB1CRBNKMT2A | |
| SCHEMBL832130 | 0.78 | ALDH1A1 (0.51) | SMN1; SMN2OPRM1ALDH1A1RPS6KB1ROCK1 | |
| SCHEMBL15160572 | 0.78 | ALOX15 (0.52) | SMN1; SMN2ALDH1A1GAADDB1CRBN | |
| SCHEMBL29794895 | 0.77 | KDM4E (0.45) | TP53ALDH1A1GAAKMT2A | |
| SCHEMBL9915108 | 0.73 | TP53 (0.43) | TP53SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL830812 | 0.72 | MAPT (0.49) | SMN1; SMN2ALDH1A1CYP2D6LMNAKMT2A | |
| SCHEMBL11634591 | 0.72 | TP53 (0.46) | TP53OPRM1OPRD1OPRK1OGFRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030127-A1 | COMPOSITION COMPRISING AT LEAST ONE SUBSTITUTED CARBOCYANINE DERIVATIVE, KERATIN FIBRE TREATMENT METHOD USING SAME, ASSOCIATED DEVICE AND USE THEREOF | L'OREAL (FR) | 2006-03-23 | — | — | WO | disclosed |