Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 4/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799094 | 0.98 | L3MBTL1 (0.38) | PTGS2L3MBTL1MGLLPDE4BHSD11B1 | |
| SCHEMBL5797074 | 0.90 | PTGS2 (0.47) | PTGS2 | |
| SCHEMBL5800291 | 0.90 | LMNA (0.39) | HSD11B1ELANEALDH1A1KDM4E | |
| SCHEMBL5798472 | 0.89 | PTGS2 (0.38) | PTGS2MGLLHSD11B1ALDH1A1 | |
| SCHEMBL5554435 | 0.89 | PTGS2 (0.38) | PTGS2MGLLHSD11B1 | |
| SCHEMBL5822590 | 0.89 | PTGS2 (0.38) | PTGS2MGLL | |
| SCHEMBL5800883 | 0.89 | PTGS2 (0.45) | PTGS2 | |
| SCHEMBL5820012 | 0.88 | PTGS2 (0.36) | PTGS2MGLLHSD11B1ALDH1A1 | |
| SCHEMBL5798160 | 0.87 | L3MBTL1 (0.37) | PTGS2L3MBTL1MGLLPDE4BHSD11B1 | |
| SCHEMBL5797314 | 0.87 | TSHR (0.37) | PTGS2MGLLHSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |