Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.83 |
| ▸ | CNR2 | P34972 | 4/20 | 0.83 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.74 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.70 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.70 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.70 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.70 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | PTGES | O14684 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801098 | 0.92 | CNR1 (0.73) | CNR1CNR2HIF1ALMNACYP1A2 | |
| SCHEMBL4322359 | 0.89 | CNR2 (0.85) | CNR1CNR2HIF1ALMNACYP1A2 | |
| SCHEMBL3240118 | 0.88 | HIF1A (0.72) | CNR1CNR2HIF1ALMNACYP1A2 | |
| SCHEMBL1082631 | 0.85 | HIF1A (1.00) | HIF1ALMNACYP1A2CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL8646699 | 0.84 | HIF1A (0.98) | HIF1ALMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL18500885 | 0.84 | AKR1C3 (0.79) | CNR2HIF1ALMNACYP1A2CYP2D6 | |
| SCHEMBL3240332 | 0.84 | AKR1C3 (0.75) | CNR1CNR2HIF1ALMNACYP1A2 | |
| SCHEMBL29454968 | 0.84 | AKR1C3 (0.75) | CNR1CNR2HIF1ALMNACYP1A2 | |
| Indomethacin SCHEMBL28072579 | 0.84 | PTGS2 (0.98) | CNR2HIF1ALMNACYP1A2CYP2D6 | |
| SCHEMBL8932650 | 0.84 | CNR2 (1.00) | CNR1CNR2HIF1ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710086-B1 | CHEMICALLY MODIFIED PHARMACOLOGICALLY ACTIVE AGENT IN CARRIER; REDUCE THE DAMAGE TO THE GASTROINTESTINAL TRACT | MEDINOX, INC. | 2004-03-23 | — | — | US | disclosed |
| US-6361792-B1 | Lipid dispersions and methods of use | ALLIANCE PHARMACEUTICAL CORP. | 2002-03-26 | — | — | US | disclosed |
| US-4200631-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIULCER AGENTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1980-04-29 | — | — | US | disclosed |