Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102532 | 0.84 | ALDH1A1 (0.54) | LMNATDP1KMT2AMAPTMAPK1 | |
| SCHEMBL5802171 | 0.83 | LMNA (0.45) | LMNATDP1HTTVCAM1POLB | |
| SCHEMBL5802613 | 0.81 | HTT (0.48) | LMNATDP1HTTVCAM1KMT2A | |
| SCHEMBL5802615 | 0.81 | HTT (0.46) | LMNATDP1HTTVCAM1KMT2A | |
| SCHEMBL5803271 | 0.80 | HTT (0.43) | LMNATDP1HTTVCAM1POLB | |
| SCHEMBL7684242 | 0.77 | ALDH1A1 (0.64) | LMNATDP1KMT2AMAPTMAPK1 | |
| SCHEMBL5804519 | 0.77 | HTT (0.48) | LMNATDP1HTTVCAM1KMT2A | |
| SCHEMBL5804503 | 0.77 | HTT (0.48) | LMNATDP1HTTVCAM1KMT2A | |
| SCHEMBL948375 | 0.76 | ALDH1A1 (0.51) | LMNATDP1KMT2APOLBMAPT | |
| SCHEMBL5803274 | 0.75 | HTT (0.45) | LMNATDP1HTTVCAM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006079857-A1 | DIARYL ACETIC ACID DERIVATIVES AND THE PREPARATION THEREOF | SANOFI-AVENTIS (FR) | 2006-08-03 | — | — | WO | disclosed |