Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5802171 | 0.85 | LMNA (0.45) | HTTLMNATDP1VCAM1POLB | |
| SCHEMBL5801377 | 0.80 | LMNA (0.47) | HTTLMNATDP1VCAM1POLB | |
| SCHEMBL5803274 | 0.79 | HTT (0.45) | HTTLMNATDP1VCAM1POLB | |
| SCHEMBL5804519 | 0.77 | HTT (0.48) | HTTLMNATDP1VCAM1POLB | |
| SCHEMBL5804503 | 0.77 | HTT (0.48) | HTTLMNATDP1VCAM1POLB | |
| SCHEMBL5802615 | 0.75 | HTT (0.46) | HTTLMNATDP1VCAM1POLB | |
| SCHEMBL5802613 | 0.75 | HTT (0.48) | HTTLMNATDP1VCAM1POLB | |
| SCHEMBL4446049 | 0.72 | VCAM1 (0.53) | LMNAVCAM1POLBARPELP1 | |
| SCHEMBL4433135 | 0.72 | VCAM1 (0.53) | LMNAVCAM1POLBARPELP1 | |
| SCHEMBL11137980 | 0.71 | ALDH1A1 (0.61) | HTTLMNATDP1VCAM1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006079857-A1 | DIARYL ACETIC ACID DERIVATIVES AND THE PREPARATION THEREOF | SANOFI-AVENTIS (FR) | 2006-08-03 | — | — | WO | disclosed |