Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820016 | 1.00 | KMT2A (0.37) | KMT2AGAAMAPTALDH1A1RAB9A | |
| SCHEMBL5798028 | 0.91 | KMT2A (0.43) | KMT2AGAAMAPTALDH1A1RAB9A | |
| SCHEMBL5799304 | 0.91 | KMT2A (0.43) | KMT2AGAAMAPTALDH1A1RAB9A | |
| SCHEMBL5801142 | 0.90 | CYP26A1 (0.40) | KMT2AMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL5800376 | 0.90 | CYP26A1 (0.40) | KMT2AMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL5797762 | 0.89 | EPHX2 (0.41) | KMT2AGAAMAPTALDH1A1RAB9A | |
| SCHEMBL5814731 | 0.87 | ALDH1A1 (0.40) | KMT2AMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL5819711 | 0.85 | MAPT (0.37) | KMT2AMAPTALDH1A1HPGDTHRB | |
| SCHEMBL5797971 | 0.82 | GPR35 (0.35) | KMT2AGAAMAPTALDH1A1TP53 | |
| SCHEMBL5797287 | 0.82 | GPR35 (0.35) | KMT2AGAAMAPTALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | claimed |
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | disclosed |