Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.60 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798211 | 0.82 | CHEK1 (0.62) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL23758529 | 0.77 | CHEK1 (0.56) | PTPRCCHEK1GPR35MEN1KMT2A | |
| SCHEMBL1960575 | 0.75 | PTPRC (1.00) | PTPRCMEN1KMT2AL3MBTL1MAOA | |
| SCHEMBL5798092 | 0.74 | CHEK1 (0.78) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL31472931 | 0.74 | GPR3 (0.75) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL29368441 | 0.74 | GPR3 (0.75) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL472539 | 0.74 | GPR3 (0.75) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL5801828 | 0.73 | CHEK1 (0.54) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL2622517 | 0.73 | GPR3 (0.61) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL22843340 | 0.71 | CHEK1 (0.49) | CHEK1GPR35MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060774-A2 | AGENTS THAT INHIBIT FLAVIVIRUS REPLICATION AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-06-08 | — | — | WO | disclosed |