Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5802848 | 0.87 | TSHR (0.46) | NPSR1TDP1POLBCYP2C19TSHR | |
| SCHEMBL5802845 | 0.87 | TSHR (0.46) | NPSR1TDP1POLBCYP2C19TSHR | |
| SCHEMBL5802478 | 0.87 | LMNA (0.46) | NPSR1TDP1POLBCYP2C19MAPK1 | |
| SCHEMBL5802840 | 0.87 | TSHR (0.46) | NPSR1TDP1POLBCYP2C19TSHR | |
| SCHEMBL5801804 | 0.87 | LMNA (0.46) | NPSR1TDP1POLBCYP2C19MAPK1 | |
| SCHEMBL5806417 | 0.87 | LMNA (0.46) | NPSR1TDP1POLBCYP2C19MAPK1 | |
| SCHEMBL5802842 | 0.87 | TSHR (0.46) | NPSR1TDP1POLBCYP2C19TSHR | |
| SCHEMBL5813834 | 0.78 | LMNA (0.32) | TDP1POLBGAALMNAMAPT | |
| SCHEMBL5804956 | 0.78 | LMNA (0.46) | NPSR1TDP1POLBCYP2C19MAPK1 | |
| SCHEMBL5803222 | 0.78 | LMNA (0.46) | NPSR1TDP1POLBCYP2C19MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006079857-A1 | DIARYL ACETIC ACID DERIVATIVES AND THE PREPARATION THEREOF | SANOFI-AVENTIS (FR) | 2006-08-03 | — | — | WO | disclosed |