Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL29054307 | 0.96 | GSR (0.40) | GSRDPP4DPP8DPP9DPP7 | |
| D-Glutamate SCHEMBL29083846 | 0.91 | GSR (0.33) | GSRSLC7A5 | |
| Lysine SCHEMBL28413064 | 0.90 | GSR (0.46) | GSRDPP4DPP8DPP9DPP7 | |
| Lysine SCHEMBL10428569 | 0.90 | GSR (0.39) | GSRDPP4DPP8DPP9DPP7 | |
| Lysine SCHEMBL659927 | 0.89 | GSR (0.47) | GSRDPP4DPP8DPP9DPP7 | |
| Lysine SCHEMBL27639977 | 0.89 | GSR (0.47) | GSRDPP4DPP8DPP9DPP7 | |
| Lysine SCHEMBL8205468 | 0.88 | GSR (0.43) | GSRDPP4DPP8DPP9DPP7 | |
| Lysine SCHEMBL4450695 | 0.88 | GSR (0.48) | GSRSLC7A5DPP4DPP8DPP9 | |
| Lysine SCHEMBL20641479 | 0.88 | GSR (0.48) | GSRSLC7A5DPP4DPP8DPP9 | |
| Lysine SCHEMBL29253065 | 0.88 | GSR (0.48) | GSRSLC7A5DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006048339-A2 | COSMETIC COMPOSITION COMRISING AN ACTIVE AGENT AND A UREA COMPOUND | L'ORÉAL (FR) | 2006-05-11 | — | — | WO | claimed |
| WO-2024065613-A1 | COSMETIC COMPOSITION FOR CARING KERATIN MATERIAL | L'OREAL (FR) | 2024-04-04 | — | — | WO | disclosed |
| WO-2006048339-A2 | COSMETIC COMPOSITION COMRISING AN ACTIVE AGENT AND A UREA COMPOUND | L'ORÉAL (FR) | 2006-05-11 | — | — | WO | disclosed |