Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16921629 | 0.75 | ALOX5 (0.41) | NPC1GAAALDH1A1MAPTRAB9A | |
| SCHEMBL6130010 | 0.74 | MAPK1 (0.39) | NPC1GAAALDH1A1MAPTRAB9A | |
| SCHEMBL9238085 | 0.73 | NPC1 (0.41) | NPC1GAAALDH1A1MAPTRAB9A | |
| SCHEMBL7118342 | 0.65 | MAPK1 (0.45) | NPC1GAAALDH1A1MAPTRAB9A | |
| SCHEMBL8198856 | 0.65 | KDM4E (0.45) | NPC1GAAALDH1A1MAPTRAB9A | |
| SCHEMBL24122438 | 0.64 | MAPT (0.44) | NPC1GAAALDH1A1MAPTRAB9A | |
| SCHEMBL30032251 | 0.64 | NOS3 (0.44) | NPC1GAAALDH1A1MAPTRAB9A | |
| SCHEMBL5657009 | 0.64 | KDM4E (0.43) | NPC1GAAALDH1A1MAPTRAB9A | |
| SCHEMBL15469493 | 0.64 | MAPT (0.43) | NPC1GAAALDH1A1MAPTRAB9A | |
| SCHEMBL28861826 | 0.64 | KDM4E (0.43) | NPC1GAAALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006066260-A2 | COMPOSITIONS OF AND METHODS FOR PRODUCING PHOSPHORUS-CHIRAL MONOMERS AND OLIGOMERS | THIOSENSE, INC. (US) | 2006-06-22 | — | — | WO | disclosed |