Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 8/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4080267 | 0.88 | FAAH (0.48) | FAAHCNR1CNR2 | |
| SCHEMBL4079397 | 0.87 | RBP4 (0.40) | RBP4FAAHCNR1CNR2 | |
| SCHEMBL4089334 | 0.87 | CNR1 (0.40) | RBP4FAAHCNR1CNR2 | |
| SCHEMBL4079103 | 0.87 | RBP4 (0.37) | RBP4FAAHCNR1CNR2KMT2A | |
| SCHEMBL5821503 | 0.87 | FAAH (0.37) | RBP4FAAHCNR1SCDTP53 | |
| SCHEMBL4075637 | 0.86 | CNR1 (0.48) | RBP4FAAHCNR1 | |
| SCHEMBL29574824 | 0.86 | CNR1 (0.48) | RBP4FAAHCNR1 | |
| SCHEMBL4084791 | 0.83 | FAAH (0.47) | FAAHCNR1CNR2 | |
| SCHEMBL4084837 | 0.82 | CNR1 (0.51) | RBP4FAAHCNR1CNR2 | |
| SCHEMBL4083772 | 0.81 | FAAH (0.49) | FAAHCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620395-A1 | AZETIDINECARBOXAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CB1 RECEPTOR MEDIATED DISORDERS | VERNALIS RESEARCH LIMITED (GB) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004096763-A1 | AZETIDINECARBOXAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CB1 RECEPTOR MEDIATED DISORDERS | VERNALIS RESEARCH LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |