Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | LIPA | P38571 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871408 | 1.00 | MEN1 (0.41) | MEN1KMT2AHTTL3MBTL1TSHR | |
| SCHEMBL4570341 | 0.90 | EPHX2 (0.37) | MEN1KMT2AHTTL3MBTL1EPHX2 | |
| SCHEMBL1981954 | 0.90 | EPHX2 (0.37) | MEN1KMT2AHTTL3MBTL1EPHX2 | |
| SCHEMBL472084 | 0.82 | EPHX2 (0.44) | EPHX2 | |
| SCHEMBL3933914 | 0.82 | — | — | |
| SCHEMBL12311623 | 0.80 | EPHX2 (0.35) | MEN1KMT2AHTTL3MBTL1EPHX2 | |
| SCHEMBL14952788 | 0.80 | MEN1 (0.41) | MEN1KMT2AHTTL3MBTL1TSHR | |
| SCHEMBL30754364 | 0.80 | MEN1 (0.41) | MEN1KMT2AHTTL3MBTL1TSHR | |
| SCHEMBL3043547 | 0.79 | TDP1 (0.40) | MEN1KMT2AHTTL3MBTL1TSHR | |
| SCHEMBL14609409 | 0.77 | EPHX2 (0.39) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61263944-A | — | — | None | — | — | JP | disclosed |
| US-9060943-B2 | Compositions comprising trans-tert-butyl cyclohexanol as skin irritation-reducing agent | SYMRISE AG (DE) | 2015-06-23 | — | — | US | disclosed |
| US-20120121737-A1 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | SYMRISE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| EP-2416766-A2 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | Symrise AG (DE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2009087242-A2 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | SYMRISE GMBH & CO. KG (DE) | 2009-07-16 | — | — | WO | disclosed |
| US-4767867-A | 5-(alkoxyalkyl)-3-phenyl-3-(1H-imidazol-1-ylmethyl)-2-methylisoxazolidines | PENNWALT CORPORATION (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0257391-A2 | 5-Substituted-3-phenyl-3-(1H-imidazol-1-ylmethyl)-2-methylisoxazolidines | FISONS CORPORATION (US) | 1988-03-02 | — | — | EP | disclosed |
| JP-S61263944-A | CIS(OR TRANS)-1-ALLYLOXY-4-TERT-BUTYLCYCLOHEXANE AND PERFUME COMPOSITION CONTAINING SAME | KAO CORP | 1986-11-21 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120121737-A1 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | TERT, CUTA, TRPA1 | MEN1 4238/4885KMT2A 3149/4885HTT 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.