Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27885694 | 0.81 | ALDH1A1 (0.47) | TDP1SMN1; SMN2KDM4ETSHRMEN1 | |
| SCHEMBL273853 | 0.80 | ALDH1A1 (0.49) | TDP1HTTSMN1; SMN2KDM4ETSHR | |
| SCHEMBL10871408 | 0.79 | MEN1 (0.41) | APOBEC3AAPOBEC3GHTTSMN1; SMN2KDM4E | |
| SCHEMBL580205 | 0.79 | MEN1 (0.41) | APOBEC3AAPOBEC3GHTTSMN1; SMN2KDM4E | |
| SCHEMBL11147394 | 0.74 | MEN1 (0.43) | APOBEC3AAPOBEC3GHTTSMN1; SMN2KDM4E | |
| SCHEMBL6870662 | 0.72 | HSD11B1 (0.36) | APOBEC3AAPOBEC3GHTTSMN1; SMN2KDM4E | |
| SCHEMBL30324749 | 0.71 | ITGB3 (0.39) | TDP1APOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL27652842 | 0.71 | APOBEC3A (0.48) | APOBEC3AAPOBEC3GHTTSMN1; SMN2KDM4E | |
| SCHEMBL352105 | 0.70 | APOBEC3A (0.39) | APOBEC3AAPOBEC3GHTTSMN1; SMN2KDM4E | |
| SCHEMBL1981954 | 0.70 | EPHX2 (0.37) | HTTMEN1KMT2AL3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168941-A1 | Novel Glycolate derivatives | V. Mane Fils (FR) | 2010-03-31 | — | — | EP | disclosed |