Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | TERT | O14746 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5803322 | 0.85 | KDM4E (0.48) | KDM4EL3MBTL1CYP19A1TERTACHE | |
| SCHEMBL6001943 | 0.78 | TERT (0.44) | KDM4EL3MBTL1TERTACHELMNA | |
| SCHEMBL12402661 | 0.76 | CYP19A1 (0.80) | KDM4EL3MBTL1CYP19A1ACHELMNA | |
| SCHEMBL22648996 | 0.76 | BIRC5 (0.50) | L3MBTL1TERTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL12014898 | 0.76 | KDM4E (0.56) | KDM4EL3MBTL1CYP19A1TERTACHE | |
| SCHEMBL26997351 | 0.73 | DHODH (0.58) | KDM4EL3MBTL1CYP19A1ACHELMNA | |
| SCHEMBL14259395 | 0.73 | TERT (0.47) | KDM4ETERTACHELMNASMN1; SMN2 | |
| SCHEMBL22648975 | 0.72 | ALDH1A1 (0.56) | KDM4EL3MBTL1TERTLMNAHPGD | |
| SCHEMBL16344606 | 0.72 | CYP3A4 (0.45) | KDM4ECYP19A1TERTLMNAHPGD | |
| SCHEMBL6001202 | 0.72 | ACP1 (0.54) | KDM4EACHELMNAACP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | claimed |
| WO-2006058201-A2 | HETEROCYCLIC AND BICYCLIC COMPOUNDS, COMPOSITIONS AND METHODS | REDDY US THERAPEUTICS, INC. (US) | 2006-06-01 | — | — | WO | claimed |
| US-20080064878-A1 | Low cost, high yield, industrial scale reaction of 4-halopyridine and indole derivatives in presence of strong organic base; heavy metal catalyst free | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20080064878-A1 | Low cost, high yield, industrial scale reaction of 4-halopyridine and indole derivatives in presence of strong organic base; heavy metal catalyst free | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | KDM4E 2893/4885L3MBTL1 4021/4885CYP19A1 863/4885 |
| US-20080064878-A1 | Low cost, high yield, industrial scale reaction of 4-halopyridine and indole derivatives in presence of strong organic base; heavy metal catalyst free | IDO1, IDO2, TDO2 | KDM4E 451/4885L3MBTL1 4000/4885CYP19A1 3783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.