Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 16/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 16/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 16/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 13/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5803270 | 0.90 | OPRM1 (0.46) | OPRM1OPRK1OPRL1OPRD1ENPP2 | |
| SCHEMBL5801972 | 0.89 | OPRM1 (0.51) | OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL5801129 | 0.86 | ENPP2 (0.55) | OPRM1OPRK1OPRL1OPRD1ENPP2 | |
| SCHEMBL5781813 | 0.85 | OPRM1 (0.50) | OPRM1OPRK1OPRL1OPRD1ENPP2 | |
| SCHEMBL6474759 | 0.83 | OPRM1 (0.48) | OPRM1OPRK1OPRL1OPRD1ENPP2 | |
| SCHEMBL5802411 | 0.82 | ENPP2 (0.46) | OPRM1OPRK1OPRL1OPRD1ENPP2 | |
| SCHEMBL5799004 | 0.81 | ENPP2 (0.50) | OPRM1OPRK1OPRL1OPRD1ENPP2 | |
| SCHEMBL5799989 | 0.80 | ENPP2 (0.44) | OPRM1OPRK1OPRL1OPRD1ENPP2 | |
| SCHEMBL5799178 | 0.79 | ENPP2 (0.43) | OPRM1OPRK1OPRL1OPRD1ENPP2 | |
| SCHEMBL5780332 | 0.77 | OPRM1 (0.47) | OPRM1OPRK1OPRL1OPRD1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329451-B1 | SPIRO COMPOUNDS AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES (JP) | 2006-08-23 | — | — | EP | disclosed |
| EP-1329451-A1 | SPIRO COMPOUNDS AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2003-07-23 | — | — | EP | disclosed |