SCHEMBL580293

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16473327	0.81	PIK3C3 (0.54)	PIK3C3TYK2
	SCHEMBL21317876	0.77	DHODH (0.39)	MEN1NPC1RAB9AKMT2AMAPT
	SCHEMBL1265630	0.76	CYP1A2 (0.60)	KDRTEKROCK2LCKBRAF
	SCHEMBL580437	0.75	ADORA2B (0.42)	PDE10AMEN1NPC1RAB9AKMT2A
	SCHEMBL1264943	0.74	DYRK1A (0.45)	PDE10A
	SCHEMBL21317868	0.74	BACE1 (0.40)	MEN1NPC1RAB9AKMT2ADHODH
	SCHEMBL6507496	0.73	CYP1A2 (0.60)	MAPK10CYP1A2CYP2C19CYP2D6HSD17B10
	SCHEMBL1264742	0.72	KDR (0.57)	KDRTEKPDE10A
	SCHEMBL2480308	0.72	FDPS (0.53)	MAPK10MAPT
	SCHEMBL2459179	0.71	DHODH (0.43)	CYP1A2CYP2C19CYP2D6CYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.