SCHEMBL580437

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28357121	0.79	MAP4K4 (0.53)	CYP11B2MAPTNPC1RAB9AMEN1
	SCHEMBL30427602	0.76	ADORA2B (0.48)	ADORA2BADORA2ANQO2MAPTIDO1
	SCHEMBL15638509	0.76	RAB9A (0.54)	CYP11B2MAPTNPC1RAB9AKMT2A
	SCHEMBL2459179	0.75	DHODH (0.43)	MAPTNPC1RAB9AMEN1KMT2A
	SCHEMBL1264943	0.75	DYRK1A (0.45)	DYRK1AIDO1PDE10A
	SCHEMBL580292	0.75	CTSA (0.40)	MAPTNPC1RAB9AMEN1KMT2A
	SCHEMBL580293	0.75	PIK3C3 (0.42)	MAPTNPC1RAB9AMEN1KMT2A
	SCHEMBL22068158	0.73	IDO1 (0.55)	ADORA2BNFATC1DYRK1AADORA2AMAPT
	SCHEMBL25280685	0.73	MAPK1 (0.47)	ADORA2BNFATC1DYRK1AADORA2AIDO1
	SCHEMBL28493426	0.73	ALDH1A1 (0.47)	ADORA2BNFATC1DYRK1ANPC1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.