Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 6/20 | 0.62 |
| ▸ | CES1 | P23141 | 6/20 | 0.62 |
| ▸ | BCHE | P06276 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31537534 | 0.80 | CES2 (0.71) | CES2CES1BCHEHPGDALB | |
| SCHEMBL6441124 | 0.80 | CES2 (0.71) | CES2CES1BCHEHPGDALB | |
| SCHEMBL22540 | 0.80 | CES2 (0.58) | CES2CES1BCHEHPGDALB | |
| SCHEMBL5845101 | 0.78 | CES2 (0.56) | CES2CES1BCHEHPGDALB | |
| SCHEMBL489916 | 0.78 | CES2 (0.59) | CES2CES1BCHEHPGDALB | |
| SCHEMBL16953030 | 0.77 | CES2 (0.60) | CES2CES1BCHEHPGDALB | |
| SCHEMBL3184940 | 0.77 | CES2 (1.00) | CES2CES1BCHEHPGDALB | |
| SCHEMBL3440833 | 0.77 | CES2 (0.74) | CES2CES1BCHEHPGDALB | |
| SCHEMBL28557442 | 0.77 | CES2 (0.54) | CES2CES1BCHEHPGDALB | |
| SCHEMBL15920914 | 0.77 | CES2 (0.54) | CES2CES1BCHEHPGDALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023160316-A1 | PYRETHROID COMPOUND CONTAINING DOUBLE BONDS AND CYANO GROUPS, SYNTHESIS METHOD THEREFOR, AND APPLICATION THEREOF | 江苏扬农化工股份有限公司 | 2023-08-31 | — | — | WO | claimed |
| CN-116375604-A | Double-bond cyano-containing pyrethroid compound, and synthetic method and application thereof | 江苏扬农化工股份有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-111362962-A | Tetrafluorobenzyl norcantharidin carboxylate and synthesis method thereof | 遵义医科大学 | 2020-07-03 | — | — | CN | claimed |
| EP-2922401-B1 | USE OF A COMPOUND COMPRISING A POLYFLUOROBENZYL MOIETY AGAINST INSECTICIDE-RESISTANT BED-BUGS | BAYER CROPSCIENCE AG (DE) | 2018-04-25 | — | — | EP | claimed |
| EP-2417972-B1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING BURN INJURIES | NEUROTECH PHARMACEUTICALS CO LTD (KR) | 2017-06-14 | — | — | EP | claimed |
| EP-1551793-B1 | TETRAFLUOROBENZYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ACUTE AND CHRONIC NEURODEGENERATIVE DISEASES IN CENTRAL NERVOUS SYSTEM CONTAINING THE SAME | AMKOR PHARMA INC (US) | 2016-01-20 | — | — | EP | claimed |
| US-20120301551-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING NEURONAL DEATH OR NEUROLOGICAL DYSFUNCTION | NEUROTECH PHARMACEUTICALS CO., LTD. (KR) | 2012-11-29 | — | — | US | claimed |
| US-20120289602-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING BURN INJURIES | ARAONTECH CO., LTD. (KR) | 2012-11-15 | — | — | US | claimed |
| CN-102421430-A | Pharmaceutical composition for treating or preventing burn | NEUROTECH PHARMACEUTICALS CO L | 2012-04-18 | — | — | CN | claimed |
| EP-2417972-A2 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING BURN INJURIES | Neurotech Pharmaceuticals Co., Ltd. (KR) | 2012-02-15 | — | — | EP | claimed |
| CN-1738627-A | Method for inhibiting necrosis induced by neurotrophic factor | NEUROTECH PHARMACEUTICALS CO L (KR) | 2006-02-22 | — | — | CN | claimed |
| EP-1592429-A1 | METHOD FOR INHIBITION OF NECROSIS INDUCED BY NEUROTROPHIN | Neurotech Pharmaceuticals Co., Ltd. (KR) | 2005-11-09 | — | — | EP | claimed |
| US-20050239896-A1 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same | NEUROTECH CO., LTD | 2005-10-27 | — | — | US | claimed |
| CN-1668576-A | Tetrafluorobenzyl derivatives and pharmaceutical composition for treating and preventing acute and chronic neurodegenerative diseases of central nervous system containing the same | NEUROTECH CO LTD (KR) | 2005-09-14 | — | — | CN | claimed |
| WO-2004064844-A9 | METHOD FOR INHIBITION OF NECROSIS INDUCED BY NEUROTROPHIN | NEUROTECH PHARMACEUTICALS CO L (KR) | 2005-08-25 | — | — | WO | claimed |
| US-6927303-B2 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same | NEUROTECH CO., LTD. (KR) | 2005-08-09 | — | — | US | claimed |
| EP-1551793-A1 | TETRAFLUOROBENZYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ACUTE AND CHRONIC NEURODEGENERATIVE DISEASES IN CENTRAL NERVOUS SYSTEM CONTAINING THE SAME | Neurotech Co., Ltd. (KR) | 2005-07-13 | — | — | EP | claimed |
| US-20040209957-A1 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same | NEUROTECH PHARMACEUTICALS CO., LTD. (KR) | 2004-10-21 | — | — | US | claimed |
| WO-2004064844-A1 | METHOD FOR INHIBITION OF NECROSIS INDUCED BY NEUROTROPHIN | NEUROTECH PHARMACEUTICALS CO., LTD. (KR) | 2004-08-05 | — | — | WO | claimed |
| WO-2004000786-A1 | TETRAFLUOROBENZYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ACUTE AND CHRONIC NEURODEGENERATIVE DISEASES IN CENTRAL NERVOUS SYSTEM CONTAINING THE SAME | NEUROTECH CO., LTD. (KR) | 2003-12-31 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120301551-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING NEURONAL DEATH OR NEUROLOGICAL DYSFUNCTION | BCL2, BAX, SMN1; SMN2 | CES2 3610/4885CES1 4585/4885BCHE 1012/4885 |
| US-20050239896-A1 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same | HTT, BDNF, APP | CES2 2830/4885CES1 2683/4885BCHE 122/4885 |
| US-20120289602-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING BURN INJURIES | CTSA, CFTR, CPT1A | CES2 996/4885CES1 346/4885BCHE 688/4885 |
| US-20040209957-A1 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same | HTT, BDNF, APP | CES2 2830/4885CES1 2683/4885BCHE 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.