SCHEMBL22540

SCHEMBL22540

FC(F)=C(F)c1cccc(F)c1F

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 0.58
CES1 P23141 5/20 0.58
BCHE P06276 1/20 0.58
HPGD P15428 2/20 0.44
ALB P02768 1/20 0.39
KAT6A Q92794 2/20 0.38
ALDH1A1 P00352 2/20 0.37
ALOX15 P16050 1/20 0.37
ATM Q13315 1/20 0.35
GAA P10253 1/20 0.33
CTSL P07711 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
DCLK1 O15075 1/20 0.31
DYRK3 O43781 1/20 0.31
ROCK2 O75116 1/20 0.31
PRKD3 O94806 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL28242721 0.90 CES2 (0.48) CES2CES1BCHEHPGDALB
SCHEMBL21218733 0.87 CES2 (0.41) CES2CES1BCHEHPGDALB
SCHEMBL5845101 0.84 CES2 (0.56) CES2CES1BCHEHPGDALB
Styrene SCHEMBL8333795 0.82 ALDH1A1 (0.45) CES2CES1BCHEHPGDALB
Methacrylic Acid SCHEMBL9728600 0.82 CES2 (0.50) CES2CES1BCHEHPGDALB
SCHEMBL28557442 0.82 CES2 (0.54) CES2CES1BCHEHPGDALB
SCHEMBL970209 0.80 CES2 (0.54) CES2CES1BCHEHPGDALB
SCHEMBL580352 0.80 CES2 (0.62) CES2CES1BCHEHPGDALB
SCHEMBL8470422 0.80 CES2 (0.40) CES2CES1BCHEHPGD
SCHEMBL1672688 0.79 CES2 (0.42) CES2CES1BCHEHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2911 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6352782-B1 None US claimed
EP-4419618-B1 FLUORESCENT BARCODED QUANTUM DOTS FOR DRILLING DEPTH CORRELATION SAUDI ARABIAN OIL CO (SA) 2026-05-13 EP claimed
CN-121394303-B High-load composite sulfur positive electrode, preparation method thereof and lithium sulfur battery 中国铁塔股份有限公司 2026-05-12 CN claimed
US-20260055265-A1 IMPROVED IONOMER BLENDS, HIGH-TEMPERATURE POLYMER ELECTROLYTE MEMBRANES AND ELECTRODE ASSEMBLIES PENN STATE RES FOUND (US) 2026-02-26 US claimed
WO-2025145193-A9 MULTIFUNCTIONAL COMPOSITE SI AND C-BASED PARTICLES YIELD ENGINEERING SYSTEMS, INC. (US) 2026-02-05 WO claimed
US-20260035811-A1 ELECTROCHEMICAL CELL FOR CARBON DIOXIDE CONVERSION WITH IMPROVED CARBON DIOXIDE CONVERSION EFFICIENCY HYUNDAI MOTOR COMPANY (KR) 2026-02-05 US claimed
US-12509791-B2 Formation of organic electro-grafted films on the surface of electrically conductive or semi-conductive surfaces ALCHIMEDICS (FR) 2025-12-30 US claimed
US-20250357499-A1 METHOD OF MANUFACTURING MEMBRANE-ELECTRODE ASSEMBLY WITH SHORTENED INITIAL ACTIVATION TIME AND MEMBRANE-ELECTRODE ASSEMBLY HYUNDAI MOTOR CO LTD (KR) 2025-11-20 US claimed
EP-4633458-A1 SYSTEMS AND METHODS FOR ANALYTE DETECTION Adaptyx Biosciences, Inc. (US) 2025-10-22 EP claimed
CN-120192484-A Method for grafting anionic copolymer on surface of metal material through surface initiated polymerization 复旦大学 2025-06-24 CN claimed
WO-1990012043-A1 TRANSPARENT THERMOPLASTIC MOULDING MATERIAL AND ITS USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-10-18 WO claimed
EP-0361929-A2 Contact lenses AMO PUERTO RICO INC. (PR) 1990-04-04 EP claimed
EP-0253515-A2 Fluorine containing soft contact lens hydrogels OPTIMERS INC. (US) 1988-01-20 EP claimed
US-4696686-A Oxygen separating member and process for producing the same NIPPONDENSO CO., LTD. (JP) 1987-09-29 US claimed
EP-0183989-A2 Fluorine-containing graft copolymer and adhesive and composite membrane made thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-06-11 EP claimed
EP-0075004-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES McCARRY, John D. (US) 1983-03-30 EP claimed
WO-1982003397-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES MCCARRY JOHN D (US) 1982-10-14 WO claimed
US-4327202-A OF IMPROVED TOUGHNESS AND GAS PERMEABILITY McCarry, John D. (US) 1982-04-27 US claimed
US-4105598-A COVALENTLY BINDING CONJUGATE PROTEIN TO HYDROXY, AMINO, OR CARBOXY COPOLYMER BEADS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1978-08-08 US claimed
US-4035316-A HYDROXY- OR AMINE-SUBSTITUTED ACRYLIC MONOMERS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1977-07-12 US claimed