SCHEMBL5845101

SCHEMBL5845101

OC(F)=C(F)c1cccc(F)c1F

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 0.56
CES1 P23141 5/20 0.56
BCHE P06276 1/20 0.56
HPGD P15428 2/20 0.43
ALB P02768 1/20 0.42
KAT6A Q92794 2/20 0.40
ALDH1A1 P00352 1/20 0.35
ALOX15 P16050 1/20 0.35
DCLK1 O15075 1/20 0.35
DYRK3 O43781 1/20 0.35
ROCK2 O75116 1/20 0.35
PRKD3 O94806 1/20 0.35
MAP4K4 O95819 1/20 0.35
ABL1 P00519 1/20 0.35
EGFR P00533 1/20 0.35
NTRK1 P04629 1/20 0.35
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
CDK1 P06493 1/20 0.35
CSF1R P07333 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28557442 0.84 CES2 (0.54) CES2CES1BCHEHPGDALB
SCHEMBL22540 0.84 CES2 (0.58) CES2CES1BCHEHPGDALB
SCHEMBL580352 0.78 CES2 (0.62) CES2CES1BCHEHPGDALB
SCHEMBL18130110 0.77 CES2 (0.46) CES2CES1BCHEHPGDALB
SCHEMBL8383833 0.75 CES2 (0.48) CES2CES1BCHEHPGDALB
O-Xylene SCHEMBL28242721 0.75 CES2 (0.48) CES2CES1BCHEHPGDALB
SCHEMBL6441124 0.74 CES2 (0.71) CES2CES1BCHEHPGDALB
SCHEMBL16953851 0.74 CES2 (0.58) CES2CES1BCHEHPGDALB
SCHEMBL31537534 0.74 CES2 (0.71) CES2CES1BCHEHPGDALB
SCHEMBL365453 0.74 CES2 (0.71) CES2CES1BCHEHPGDALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9447220-B2 Self-assembled structures, method of manufacture thereof and articles comprising the same ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2016-09-20 US claimed
US-8822130-B2 Self-assembled structures, method of manufacture thereof and articles comprising the same THE TEXAS A&M UNIVERSITY SYSTEM (US) 2014-09-02 US claimed
US-20140142252-A1 SELF-ASSEMBLED STRUCTURES, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS LLC 2014-05-22 US claimed
US-20140141376-A1 SELF-ASSEMBLED STRUCTURES, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS LLC 2014-05-22 US claimed
US-20140142249-A1 SELF-ASSEMBLED STRUCTURES, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME THE TEXAS A&M UNIVERSITY SYSTEM 2014-05-22 US claimed
US-6872504-B2 High sensitivity X-ray photoresist MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-03-29 US claimed
US-20040110091-A1 High sensitivity X-ray photoresist MASS INSTITUTE OF TECHNOLOGY (MIT) 2004-06-10 US claimed
US-9447220-B2 Self-assembled structures, method of manufacture thereof and articles comprising the same ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2016-09-20 US disclosed
US-9223214-B2 Self-assembled structures, method of manufacture thereof and articles comprising the same THE TEXAS A&M UNIVERSITY SYSTEM (US) 2015-12-29 US disclosed
US-8822130-B2 Self-assembled structures, method of manufacture thereof and articles comprising the same THE TEXAS A&M UNIVERSITY SYSTEM (US) 2014-09-02 US disclosed
US-20140141376-A1 SELF-ASSEMBLED STRUCTURES, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS LLC 2014-05-22 US disclosed
US-20140142249-A1 SELF-ASSEMBLED STRUCTURES, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME THE TEXAS A&M UNIVERSITY SYSTEM 2014-05-22 US disclosed
US-20140142252-A1 SELF-ASSEMBLED STRUCTURES, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS LLC 2014-05-22 US disclosed
US-6919160-B2 Acrylic compounds for sub-200 nm photoresist compositions and methods for making and using same AIR PRODUCTS AND CHEMICALS, INC. (US) 2005-07-19 US disclosed
US-6872504-B2 High sensitivity X-ray photoresist MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-03-29 US disclosed
US-20050037289-A1 monomers that can be homopolymerized or copolymerized with other reactive components to make resins within sub-200 nanometer (nm) photoresist compositions VERSUM MATERIALS US, LLC 2005-02-17 US disclosed
EP-1505050-A1 Bridged carbocyclic compounds and methods of making and using same AIR PRODUCTS AND CHEMICALS, INC. (US) 2005-02-09 EP disclosed
US-20040175644-A1 Acrylic compounds for sub-200 nm photoresist compositions and methods for making and using same AIR PRODUCTS AND CHEMICALS, INC. 2004-09-09 US disclosed
EP-1449839-A2 Fluorinated acrylic compounds, methods for preparation of the compounds and photoresist compositions containing same AIR PRODUCTS AND CHEMICALS, INC. (US) 2004-08-25 EP disclosed
US-20040110091-A1 High sensitivity X-ray photoresist MASS INSTITUTE OF TECHNOLOGY (MIT) 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050037289-A1 monomers that can be homopolymerized or copolymerized with other reactive components to make resins within sub-200 nanometer (nm) photoresist compositions SUB1, CAD, PARP10 CES2 341/4885CES1 2067/4885BCHE 3858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.