SCHEMBL580400

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL581610	0.84	MAPT (0.51)	GAANPSR1ALOX5MEN1KMT2A
	SCHEMBL1752934	0.71	NPC1 (0.49)	LMNA
	SCHEMBL1752972	0.70	ACHE (0.50)	GAAMEN1KMT2AABCG2MAPT
	SCHEMBL581419	0.68	CASP1 (0.53)	MEN1KMT2AMAPTLMNAALDH1A1
	SCHEMBL13632591	0.68	VCP (0.58)	GAANPSR1ALOX5AMY1AVCP
	SCHEMBL20869723	0.67	ESR1 (0.78)	ESRRBESR1ESRRAESR2MEN1
	SCHEMBL581896	0.67	GAA (0.91)	GAANPSR1ENPP3MEN1KMT2A
	Hydrochloric Acid SCHEMBL580605	0.66	GAA (0.88)	GAANPSR1ENPP3MEN1KMT2A
	SCHEMBL7438450	0.66	MAPT (0.40)	MEN1KMT2AMAPTLMNAALDH1A1
	SCHEMBL10656197	0.65	MMP3 (0.71)	GAANPSR1ESR1ESR2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.