Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804069 | 0.85 | MAPT (0.47) | MAPTALDH1A1L3MBTL1KCNH3CA12 | |
| SCHEMBL3248804 | 0.76 | ALDH1A1 (0.61) | MAPTALDH1A1L3MBTL1KCNH3F2 | |
| SCHEMBL27850635 | 0.73 | ALDH1A1 (0.47) | MAPTALDH1A1L3MBTL1KCNH3MEN1 | |
| SCHEMBL4859876 | 0.72 | MAPT (0.56) | MAPTALDH1A1L3MBTL1KCNH3CA12 | |
| SCHEMBL632952 | 0.72 | KCNH3 (0.62) | MAPTALDH1A1L3MBTL1KCNH3 | |
| SCHEMBL232188 | 0.72 | MAPT (0.78) | MAPTALDH1A1L3MBTL1CA12CA2 | |
| SCHEMBL8579894 | 0.72 | MAPT (0.50) | MAPTALDH1A1L3MBTL1KCNH3CA12 | |
| SCHEMBL28842598 | 0.72 | ALDH1A1 (0.50) | MAPTALDH1A1L3MBTL1KCNH3CA12 | |
| SCHEMBL11212433 | 0.72 | MAPT (0.50) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7054142 | 0.71 | MAPT (0.54) | MAPTALDH1A1L3MBTL1KCNH3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005064008-A9 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS | GILEAD SCIENCES INC (US) | 2006-09-28 | — | — | WO | disclosed |