Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NCF1 | P14598 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015900 | 0.88 | KCNH3 (0.51) | KCNH3MAPTALDH1A1NCF1L3MBTL1 | |
| SCHEMBL14982724 | 0.88 | KCNH3 (0.51) | KCNH3MAPTALDH1A1NCF1L3MBTL1 | |
| SCHEMBL3681897 | 0.88 | KCNH3 (0.51) | KCNH3MAPTALDH1A1NCF1L3MBTL1 | |
| SCHEMBL6646246 | 0.87 | ALDH1A1 (0.64) | KCNH3MAPTALDH1A1L3MBTL1GAA | |
| SCHEMBL11637357 | 0.85 | MAPT (0.61) | KCNH3MAPTALDH1A1L3MBTL1GAA | |
| SCHEMBL5556493 | 0.85 | RORC (0.52) | KCNH3MAPTALDH1A1NCF1L3MBTL1 | |
| SCHEMBL11637424 | 0.84 | MAPT (0.59) | KCNH3MAPTALDH1A1L3MBTL1GAA | |
| SCHEMBL11634715 | 0.84 | MAPT (0.59) | KCNH3MAPTALDH1A1L3MBTL1GAA | |
| SCHEMBL5013171 | 0.83 | KCNH3 (0.47) | KCNH3MAPTALDH1A1NCF1MALT1 | |
| SCHEMBL3248804 | 0.81 | ALDH1A1 (0.61) | KCNH3MAPTALDH1A1L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884513-A1 | PYRAZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES COMPRISING THE SAME | Japan Tobacco, Inc. (JP) | 2008-02-06 | — | — | EP | claimed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | claimed |
| EP-0790818-B1 | KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME | OREAL (FR) | 2001-05-30 | — | — | EP | claimed |
| US-6030984-A | 7-(4-PHENOXYPHENYL)-6-OXOQUINOLIZINES AND DERIVATIVES OF TRICYCLIC RING ANALOGUES, PARTICULARLY 7-OXOTHIENO-(2,3-A)QUINOLIZINE; INHIBITING BETA-AMYLOID PEPTIDE ACTIVITY | HOFFMANN-LA ROCHE INC. (US) | 2000-02-29 | — | — | US | claimed |
| US-5869500-A | INHIBITING BETA-AMYLOID PEPTIDE ACTIVITY | HOFFMANN-LA ROCHE INC. (US) | 1999-02-09 | — | — | US | claimed |
| WO-1998025930-A2 | USE OF BI- AND TRICYCLIC PYRIDONE DERIVATIVES AGAINST ALZHEIMER'S DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 1998-06-18 | — | — | WO | claimed |
| EP-0294669-B1 | METAPHENYLENDIAMINES, PROCESS FOR THEIR PREPARATION, INTERMEDIATE COMPOUNDS AND USE OF THESE METAPHENYLENDIAMINES AS COUPLERS IN OXYDATIVE COLOURING OF KERATINIC FIBRES ESPECIALLY OF HUMAN HAIR | L'OREAL (FR) | 1991-07-17 | — | — | EP | claimed |
| EP-0295474-B1 | CHLOROMETAPHENYLENEDIAMINES, THEIR USE AS COUPLING AGENTS IN OXYDATION COLOURING OF KERATINIC FIBRES, COLOURITY COMPOSITIONS FOR HAIR CONTAINING THESE COMPOUNDS AND COLOURING PROCESS USING THESE COMPOSITIONS | L'OREAL (FR) | 1991-07-17 | — | — | EP | claimed |
| EP-0416962-A1 | Keratinous fibers dyeing process with indole dyes and oxidation dye precursors and dyeing agents | L'OREAL (FR) | 1991-03-13 | — | — | EP | claimed |
| EP-0295474-A1 | Chlorometaphenylenediamines, their use as coupling agents in oxydation colouring of keratinic fibres, colourity compositions for hair containing these compounds and colouring process using these compositions | L'OREAL (FR) | 1988-12-21 | — | — | EP | claimed |
| EP-0294669-A1 | Metaphenylendiamines, process for their preparation, intermediate compounds and use of these metaphenylendiamines as couplers in oxydative colouring of keratinic fibres especially of human hair | L'OREAL (FR) | 1988-12-14 | — | — | EP | claimed |
| EP-4692072-A1 | PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES | TOKUYAMA CORPORATION (JP) | 2026-02-11 | — | — | EP | disclosed |
| EP-4692071-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS | TOKUYAMA CORPORATION (JP) | 2026-02-11 | — | — | EP | disclosed |
| EP-4688148-A1 | SELECTIVE RAPAMYCIN ANALOGS AND USES THEREOF | Regeneron Pharmaceuticals, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-4370207-B1 | BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES INC (US) | 2025-12-17 | — | — | EP | disclosed |
| US-4048154-A | POLYAMIDE FIBERS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |
| US-4028323-A | WITH A SUBSTITUTED AMINOBENZENE | CIBA-GEIGY AG (CH) | 1977-06-07 | — | — | US | disclosed |
| US-3987026-A | POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1976-10-19 | — | — | US | disclosed |
| US-3964862-A | Process for dyeing and printing textile materials of synthetic organic fibers | CIBA-GEIGY AG (CH) | 1976-06-22 | — | — | US | disclosed |
| US-3945991-A | Heterocyclic azo compounds containing a quaternated hydrazide group | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | PYGL, GYS2, AGL | KCNH3 896/4885MAPT 4621/4885ALDH1A1 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.