Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804198 | 1.00 | TBXAS1 (0.38) | TBXAS1NR1H3PPARGPPARANR1H2 | |
| SCHEMBL3885986 | 0.85 | NR1H3 (0.34) | NR1H3PPARANR1H2NPC1RAB9A | |
| SCHEMBL3885989 | 0.85 | NR1H3 (0.34) | NR1H3PPARANR1H2NPC1RAB9A | |
| SCHEMBL6359890 | 0.76 | NR1H3 (0.33) | NR1H3NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6752629 | 0.75 | CYP1A2 (0.44) | NR1H3NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6752627 | 0.75 | CYP1A2 (0.44) | NR1H3NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL29451601 | 0.73 | SMN1; SMN2 (0.38) | NR1H3NR1H2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5801697 | 0.72 | CASP3 (0.52) | TBXAS1PPARGPPARANPC1RAB9A | |
| SCHEMBL3150010 | 0.72 | SLC22A12 (0.50) | TBXAS1PPARGPPARASLC22A12 | |
| SCHEMBL6779922 | 0.72 | PPARG (0.54) | NR1H3PPARGPPARACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006080652-A1 | PROCESS FOR PREPARING THE INTERMEDIATE COMPOUNDS FOR PPARALPHA LIGANDS | KANG HEONJOONG (KR) | 2006-08-03 | — | — | WO | disclosed |