Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | PLG | P00747 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27820695 | 0.92 | HTR2C (0.58) | LMNATHRBKMT2AALDH1A1MEN1 | |
| SCHEMBL13258632 | 0.90 | LMNA (0.65) | LMNATHRBKMT2AALDH1A1MEN1 | |
| SCHEMBL27488436 | 0.89 | HTR2C (0.50) | LMNAALDH1A1NFKB1HTR2CBLM | |
| SCHEMBL6334796 | 0.89 | HTR2C (0.50) | LMNAALDH1A1NFKB1HTR2CBLM | |
| SCHEMBL108335 | 0.87 | NPC1 (0.49) | LMNAALDH1A1NFKB1HTR2CBLM | |
| SCHEMBL25216537 | 0.85 | ALDH1A1 (0.56) | LMNATHRBKMT2AALDH1A1MEN1 | |
| SCHEMBL11847129 | 0.85 | DGKA (0.54) | LMNATHRBKMT2AALDH1A1MEN1 | |
| SCHEMBL27588223 | 0.85 | DGKA (0.54) | LMNATHRBKMT2AALDH1A1MEN1 | |
| SCHEMBL11853523 | 0.85 | DGKA (0.54) | LMNATHRBKMT2AALDH1A1MEN1 | |
| SCHEMBL3764429 | 0.85 | DGKA (0.54) | LMNATHRBKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006010084-A2 | A SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELL NUCLEI | SEGEV LABORATORIES LIMITED (IL) | 2006-01-26 | — | — | WO | disclosed |