Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.52 |
| ▸ | BRAF | P15056 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819589 | 0.88 | SRC (0.53) | SRCBRAFKDRFLT3MAPK14 | |
| SCHEMBL5820384 | 0.88 | LMNA (0.47) | MEN1KMT2AATMTP53L3MBTL1 | |
| SCHEMBL5820515 | 0.84 | BRAF (0.55) | SRCBRAFKDRFLT3MAPK14 | |
| SCHEMBL5808026 | 0.84 | SRC (0.55) | SRCBRAFKDRMAPK14TP53 | |
| SCHEMBL5817016 | 0.80 | L3MBTL1 (0.47) | SRCBRAFKDRAOC3FLT3 | |
| SCHEMBL5816696 | 0.79 | MEN1 (0.46) | MEN1KMT2ALMNA | |
| SCHEMBL5820410 | 0.79 | BRAF (0.38) | SRCBRAFKDRFLT3MAPK14 | |
| SCHEMBL5820957 | 0.76 | TP53 (0.46) | MEN1KMT2AHTTTP53LMNA | |
| SCHEMBL5805633 | 0.73 | MAPT (0.53) | KCNH2MAPK14MEN1KMT2AL3MBTL1 | |
| SCHEMBL5814956 | 0.73 | MAPK9 (0.42) | SRCBRAFKDRAOC3FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117657-A1 | TRIAZOLONE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2006-11-09 | — | — | WO | claimed |