Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 3/20 | 0.55 |
| ▸ | KDR | P35968 | 3/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819589 | 0.85 | SRC (0.53) | BRAFKDRMAPK14CSNK1A1CSNK1D | |
| SCHEMBL5804303 | 0.84 | SRC (0.52) | BRAFKDRMAPK14GCGRMAPK13 | |
| SCHEMBL5808026 | 0.81 | SRC (0.55) | BRAFKDRMAPK14GCGRKDM4E | |
| SCHEMBL5817016 | 0.77 | L3MBTL1 (0.47) | BRAFKDRMAPK14FLT3SRC | |
| SCHEMBL5816696 | 0.76 | MEN1 (0.46) | MEN1KMT2A | |
| SCHEMBL5820410 | 0.76 | BRAF (0.38) | BRAFKDRMAPK14RIPK3FLT3 | |
| SCHEMBL5820957 | 0.73 | TP53 (0.46) | KDM4ETP53MEN1KMT2A | |
| SCHEMBL5816762 | 0.72 | ALDH1A1 (0.43) | ARKDM4EMEN1GAAKMT2A | |
| SCHEMBL5820384 | 0.72 | LMNA (0.47) | KDM4ETP53MEN1GAAKMT2A | |
| SCHEMBL14839292 | 0.71 | BRAF (1.00) | BRAFKDRMAPK14CSNK1A1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117657-A1 | TRIAZOLONE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2006-11-09 | — | — | WO | claimed |