Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815218 | 0.89 | L3MBTL1 (0.48) | L3MBTL1OPRM1NPC1RAB9AGLA | |
| SCHEMBL5819589 | 0.81 | SRC (0.53) | MAPK14FLT3SRCBRAFKDR | |
| SCHEMBL5804303 | 0.80 | SRC (0.52) | L3MBTL1MAPK14FLT3SRCBRAF | |
| SCHEMBL5820515 | 0.77 | BRAF (0.55) | MAPK14FLT3SRCBRAFKDR | |
| SCHEMBL5808026 | 0.77 | SRC (0.55) | L3MBTL1MAPK14SRCBRAFKDR | |
| SCHEMBL5820410 | 0.72 | BRAF (0.38) | MAPK14FLT3SRCBRAFKDR | |
| SCHEMBL5816696 | 0.72 | MEN1 (0.46) | NPC1CYP1A2 | |
| SCHEMBL5814956 | 0.71 | MAPK9 (0.42) | MAPK14FLT3SRCBRAFKDR | |
| SCHEMBL5806904 | 0.70 | MAPK9 (0.43) | MAPK14CNR1CNR2AOC3 | |
| SCHEMBL5814608 | 0.70 | MAPK9 (0.43) | MAPK14CNR1CNR2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117657-A1 | TRIAZOLONE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2006-11-09 | — | — | WO | claimed |
| WO-2006117657-A1 | TRIAZOLONE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2006-11-09 | — | — | WO | disclosed |