Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815714 | 0.92 | — | — | |
| SCHEMBL5802171 | 0.81 | LMNA (0.45) | LMNAPOLBTDP1HTTVCAM1 | |
| SCHEMBL5806417 | 0.80 | LMNA (0.46) | LMNAPOLBTDP1HTTVCAM1 | |
| SCHEMBL5801804 | 0.80 | LMNA (0.46) | LMNAPOLBTDP1HTTVCAM1 | |
| SCHEMBL5802478 | 0.80 | LMNA (0.46) | LMNAPOLBTDP1HTTVCAM1 | |
| SCHEMBL5804422 | 0.78 | NPSR1 (0.44) | LMNAPOLBTDP1HTTMAPT | |
| SCHEMBL5802840 | 0.73 | TSHR (0.46) | LMNAPOLBTDP1HTTMAPT | |
| SCHEMBL5802842 | 0.73 | TSHR (0.46) | LMNAPOLBTDP1HTTMAPT | |
| SCHEMBL5802848 | 0.73 | TSHR (0.46) | LMNAPOLBTDP1HTTMAPT | |
| SCHEMBL5804956 | 0.73 | LMNA (0.46) | LMNAPOLBTDP1HTTVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006079857-A1 | DIARYL ACETIC ACID DERIVATIVES AND THE PREPARATION THEREOF | SANOFI-AVENTIS (FR) | 2006-08-03 | — | — | WO | disclosed |