Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | OGT | O15294 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542176 | 0.85 | OGT (0.51) | ALDH1A1MAPTPKMTSHRMAPK1 | |
| SCHEMBL11980494 | 0.75 | NOD2 (0.48) | ALDH1A1MAPTTSHRKMT2AGAA | |
| SCHEMBL20168569 | 0.72 | NR1H2 (0.46) | NR1H2NR1H3 | |
| SCHEMBL9353461 | 0.71 | TDP1 (0.54) | ALDH1A1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL9241160 | 0.71 | TDP1 (0.54) | ALDH1A1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL9353455 | 0.71 | TDP1 (0.54) | ALDH1A1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL27352197 | 0.71 | TDP1 (0.54) | ALDH1A1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL18073 | 0.71 | TDP1 (0.54) | ALDH1A1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL1624312 | 0.69 | MAPT (0.49) | ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL23168121 | 0.69 | POLB (0.46) | ALDH1A1MAPTKMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006105795-A1 | NOVEL INDOLINONE DERIVATIVES | LEO PHARMA A/S (DK) | 2006-10-12 | — | — | WO | disclosed |