Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 18/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3847463 | 0.79 | MCL1 (0.45) | — | |
| SCHEMBL16493988 | 0.77 | NR1H2 (0.36) | NR1H2NR1H3CA12CA9ELANE | |
| SCHEMBL28370896 | 0.75 | NR1H2 (0.55) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL1564740 | 0.75 | NR1H2 (0.52) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL4542454 | 0.74 | NR1H2 (0.56) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL2934486 | 0.73 | NR1H2 (0.53) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL6590160 | 0.73 | GABRG2 (0.35) | ELANE | |
| SCHEMBL5805599 | 0.72 | ALDH1A1 (0.46) | NR1H2NR1H3 | |
| SCHEMBL7902953 | 0.72 | NR1H2 (0.55) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL29781083 | 0.72 | NR1H2 (0.55) | NR1H2NR1H3CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541431-A1 | MYELOPEROXIDASE IMAGING AGENTS | The General Hospital Corporation (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018094005-A1 | MYELOPEROXIDASE IMAGING AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-24 | — | — | WO | disclosed |