Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.50 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490536 | 0.84 | GABRA1 (0.66) | GABRA1GABRB2PTGDRPTGDR2MAPT | |
| SCHEMBL2318939 | 0.80 | ERN1 (0.47) | MAPTMEN1KMT2ACYP3A4HPGD | |
| SCHEMBL249746 | 0.79 | IDO1 (0.54) | PTGDRPTGDR2MAPTCYP3A4HPGD | |
| SCHEMBL30956678 | 0.79 | IDO1 (0.54) | PTGDRPTGDR2MAPTCYP3A4HPGD | |
| SCHEMBL69697 | 0.79 | TYR (0.58) | GABRA1GABRB2MAPTMEN1KMT2A | |
| Bromide SCHEMBL28225209 | 0.78 | IDO1 (0.52) | PTGDRPTGDR2MAPTCYP3A4HPGD | |
| SCHEMBL1006107 | 0.78 | XDH (0.70) | GABRA1GABRB2MAPTMEN1KMT2A | |
| SCHEMBL8259600 | 0.78 | GABRA1 (0.52) | GABRA1GABRB2MAPTMEN1KMT2A | |
| SCHEMBL5024409 | 0.77 | HPGD (0.42) | MAPTMEN1KMT2ACYP3A4HPGD | |
| SCHEMBL18551328 | 0.77 | HSD17B10 (0.50) | MAPTMEN1KMT2ACYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358716-B1 | INHIBITORS OF FATTY ACID BINDING PROTEIN (FABP) | MERCK SHARP & DOHME (US) | 2016-01-06 | — | — | EP | disclosed |
| US-8815875-B2 | Inhibitors of fatty acid binding protein (FABP) | MERCK SHARP & DOHME CORP. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8815875-B2 | Inhibitors of fatty acid binding protein (FABP) | MERCK SHARP & DOHME CORP. (US) | 2014-08-26 | — | — | US | disclosed |
| US-20110237575-A1 | INHIBITORS OF FATTY ACID BINDING PROTEIN (FABP) | MERCK SHARP & DOHME LLC | 2011-09-29 | — | — | US | disclosed |
| US-20110237575-A1 | INHIBITORS OF FATTY ACID BINDING PROTEIN (FABP) | MERCK SHARP & DOHME LLC | 2011-09-29 | — | — | US | disclosed |
| WO-2010056631-A1 | INHIBITORS OF FATTY ACID BINDING PROTEIN (FABP) | SCHERING CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |
| WO-2006069096-A1 | SILANOL DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | PHARMACYCLICS, INC. (US) | 2006-06-29 | — | — | WO | disclosed |
| EP-0488381-B1 | Polyhydroxyphenylene ether resin and process for preparing the same | MITSUBISHI CHEM CORP (JP) | 1997-01-29 | — | — | EP | disclosed |
| EP-0530442-B1 | Process for producing a hydroxy-substituted poly (phenylene ether) resin | MITSUBISHI CHEM CORP (JP) | 1996-09-04 | — | — | EP | disclosed |
| EP-0513812-B1 | Thermoplastic resin composition | MITSUBISHI CHEM CORP (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5266673-A | Compatibilizer for polymer blends and alloys | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1993-11-30 | — | — | US | disclosed |
| US-5202409-A | POLYHYDROXYPHENYLENE ETHER RESIN AND PROCESS FOR PREPARING THE SAME | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0530442-A1 | Process for producing a hydroxy-substituted poly (phenylene ether) resin | MITSUBISHI CHEMICAL CORPORATION (JP) | 1993-03-10 | — | — | EP | disclosed |
| EP-0513812-A2 | Thermoplastic resin composition | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-11-19 | — | — | EP | disclosed |
| US-5120800-A | Boriding with borane compound having at least one boron-hydrogen bond and oxidizing | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0488381-A1 | Polyhydroxyphenylene ether resin and process for preparing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-06-03 | — | — | EP | disclosed |
| EP-0451819-A2 | Process for preparing modified-polyphenylene ether | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-10-16 | — | — | EP | disclosed |
| US-4764521-A | Leukotriene antagonists and a method of use there as | ELI LILLY AND COMPANY (US) | 1988-08-16 | — | — | US | disclosed |
| EP-0132367-B1 | LEUKOTRIENE ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1988-06-08 | — | — | EP | disclosed |
| EP-0132367-A2 | Leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1985-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237575-A1 | INHIBITORS OF FATTY ACID BINDING PROTEIN (FABP) | FABP4, FABP1, FABP3 | GABRA1 1933/4885GABRB2 1196/4885PTGDR 2445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.