Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5718432 | 0.83 | IDO1 (0.48) | CYP3A4MEN1KMT2AALOX15MAPT | |
| SCHEMBL3934466 | 0.81 | TYR (0.54) | CYP3A4MEN1KMT2AALOX15MAPT | |
| SCHEMBL2144792 | 0.78 | ALOX15 (0.38) | HPGDKMT2AALOX15MAPTHTT | |
| SCHEMBL4573203 | 0.78 | ALOX15 (0.38) | HPGDKMT2AALOX15MAPTHTT | |
| SCHEMBL2318939 | 0.77 | ERN1 (0.47) | HPGDCYP3A4MEN1KMT2AHIF1A | |
| SCHEMBL5807459 | 0.77 | GABRA1 (0.50) | HPGDCYP3A4MEN1KMT2AHIF1A | |
| SCHEMBL51173 | 0.73 | CYP3A4 (0.67) | HPGDCYP3A4MEN1KMT2AHIF1A | |
| SCHEMBL7012686 | 0.72 | HSPA5 (0.50) | HPGDCYP3A4HIF1AALOX15MAPT | |
| SCHEMBL561006 | 0.71 | CYP3A4 (0.52) | HPGDCYP3A4MEN1KMT2AHIF1A | |
| SCHEMBL28534044 | 0.70 | CYP3A4 (0.50) | HPGDCYP3A4MEN1KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1983992-A2 | 2-IMINO-BENZIMIDAZOLES | Abbott Laboratories (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007084728-A2 | 2-IMINO-BENZIMIDAZOLES | ABBOTT LABORATORIES (US) | 2007-07-26 | — | — | WO | disclosed |