SCHEMBL5808012

SCHEMBL5808012

CCCCC=C[Si](C)(OCC)OCC

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
ALDH1A1 P00352 2/20 0.33
LPAR3 Q9UBY5 3/20 0.32
LPAR2 Q9HBW0 2/20 0.32
LPAR1 Q92633 1/20 0.32
F7 P08709 1/20 0.31
F3 P13726 1/20 0.31
FAAH O00519 4/20 0.31
TRPV1 Q8NER1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5808009 1.00 TSHR (0.33) TSHRALDH1A1LPAR3LPAR2LPAR1
SCHEMBL16458882 0.94 ALDH1A1 (0.41) TSHRALDH1A1LPAR3FAAHTRPV1
SCHEMBL16458884 0.94 ALDH1A1 (0.41) TSHRALDH1A1LPAR3FAAHTRPV1
SCHEMBL22472121 0.92 FAAH (0.42) TSHRALDH1A1LPAR3FAAHTRPV1
SCHEMBL22472128 0.92 FAAH (0.42) TSHRALDH1A1LPAR3FAAHTRPV1
SCHEMBL22472130 0.92 FAAH (0.42) TSHRALDH1A1LPAR3FAAHTRPV1
SCHEMBL22472139 0.92 FAAH (0.42) TSHRALDH1A1LPAR3FAAHTRPV1
SCHEMBL22472131 0.92 FAAH (0.42) TSHRALDH1A1LPAR3FAAHTRPV1
SCHEMBL22472122 0.92 FAAH (0.42) TSHRALDH1A1LPAR3FAAHTRPV1
SCHEMBL22472127 0.92 FAAH (0.42) TSHRALDH1A1LPAR3FAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140102332-A1 FUNCTIONAL REINFORCING FILLERS MODIFIED WITH ALKENYLALKOXYSILANE AND PREPARING METHOD OF THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-04-17 US claimed
EP-4617310-A1 RUBBER COMPOSITION AND ORGANOPOLYSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-09-17 EP disclosed
US-20250282914-A1 ORGANOPOLYSILOXANE CONTAINING MERCAPTO GROUP AND ALKOXYSILYL GROUP, AND COMPOSITION COMPRISING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-09-11 US disclosed
CN-120202250-A Rubber composition and organopolysiloxane 信越化学工业株式会社 2025-06-24 CN disclosed
EP-4520778-A1 ORGANOPOLYSILOXANE CONTAINING MERCAPTO GROUP AND ALKOXYSILYL GROUP, AND COMPOSITION COMPRISING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-03-12 EP disclosed
WO-2025023143-A1 GLASS CLOTH TREATMENT LIQUID AND SURFACE TREATED GLASS CLOTH 信越化学工業株式会社 2025-01-30 WO disclosed
CN-119137191-A Organopolysiloxane containing mercapto groups and alkoxysilyl groups and composition containing the same 信越化学工业株式会社 2024-12-13 CN disclosed
WO-2024101082-A1 RUBBER COMPOSITION AND ORGANOPOLYSILOXANE 信越化学工業株式会社 2024-05-16 WO disclosed
CN-113614033-B Block-shaped boron nitride particles, heat-conductive resin composition, and heat-dissipating member 电化株式会社 2024-04-30 CN disclosed
WO-2023214526-A1 ORGANOPOLYSILOXANE CONTAINING MERCAPTO GROUP AND ALKOXYSILYL GROUP, AND COMPOSITION COMPRISING SAME 信越化学工業株式会社 2023-11-09 WO disclosed
CN-102160125-A Electroconductive particles and anisotropic electroconductive material using the same NIPPON CATALYTIC CHEM IND 2011-08-17 CN disclosed
CN-102159625-A Method for producing hydrophilized microparticles and hydrophilized microparticles obtained by the method TOYO TANSO CO 2011-08-17 CN disclosed
CN-101490138-A Fine particles, method for producing fine particles, resin composition containing fine particles, and optical film NIPPON CATALYTIC CHEM IND (JP) 2009-07-22 CN disclosed
WO-2006101263-A1 COATED FINE PARTICLE AND THEIR MANUFACTURING METHOD, AND CONDUCTIVE FINE PARTICLE NIPPON SHOKUBAI CO., LTD. (JP) 2006-09-28 WO disclosed
EP-0586241-B1 Azasilacycloalkyl functional alkoxysilanes and azasilacycloalkyl functional tetramethyldisiloxanes DOW CORNING (US) 1997-04-09 EP disclosed
EP-0586240-B1 Alkoxy endblocked polydiorganosiloxane and room temperature vulcanizable silicone elastomers made therefrom DOW CORNING (US) 1996-12-18 EP disclosed
EP-0586240-A2 Alkoxy endblocked polydiorganosiloxane and room temperature vulcanizable silicone elastomers made therefrom DOW CORNING CORPORATION (US) 1994-03-09 EP disclosed
EP-0586241-A1 Azasilacycloalkyl functional alkoxysilanes and azasilacycloalkyl functional tetramethyldisiloxanes DOW CORNING CORPORATION (US) 1994-03-09 EP disclosed
US-5276123-A Endblocking polysiloxanes DOW CORNING CORPORATION (US) 1994-01-04 US disclosed
US-5239099-A Room temperature vulcanization; noncorrosive byproducts DOW CORNING CORPORATION (US) 1993-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140102332-A1 FUNCTIONAL REINFORCING FILLERS MODIFIED WITH ALKENYLALKOXYSILANE AND PREPARING METHOD OF THE SAME TST, MSN, TELO2 TSHR 656/4885ALDH1A1 993/4885LPAR3 3048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.