Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808071 | 1.00 | LTB4R (0.34) | LTB4RLTB4R2PLA2G2AKMT2AKDM4E | |
| SCHEMBL5812350 | 0.95 | LTB4R (0.36) | LTB4RLTB4R2PLA2G2AKMT2ATHRA | |
| SCHEMBL5812353 | 0.95 | LTB4R (0.36) | LTB4RLTB4R2PLA2G2AKMT2ATHRA | |
| SCHEMBL5812485 | 0.93 | LTB4R (0.34) | LTB4RLTB4R2PLA2G2AKMT2AKDM4E | |
| SCHEMBL5812476 | 0.93 | LTB4R (0.34) | LTB4RLTB4R2PLA2G2AKMT2AKDM4E | |
| SCHEMBL5807179 | 0.92 | KMT2A (0.33) | LTB4RPLA2G2AKMT2AALDH1A1THRA | |
| SCHEMBL6598919 | 0.84 | S1PR1 (0.36) | LTB4RLTB4R2PLA2G2AKMT2AKDM4E | |
| SCHEMBL6598918 | 0.84 | S1PR1 (0.36) | LTB4RLTB4R2PLA2G2AKMT2AKDM4E | |
| SCHEMBL5810585 | 0.83 | PLA2G2A (0.41) | PLA2G2AKMT2ATHRATHRBHDAC3 | |
| SCHEMBL5813873 | 0.81 | PLA2G2A (0.36) | PLA2G2AKMT2AHDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006046683-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AS LEUKOTRIENE AND PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2006-05-04 | — | — | WO | disclosed |