Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 5/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810585 | 0.90 | PLA2G2A (0.41) | PLA2G2AKMT2AICMTAKR1C3PPARG | |
| SCHEMBL6598709 | 0.84 | THRA (0.44) | PLA2G2AKMT2AICMTPPARGPPARD | |
| SCHEMBL6599665 | 0.84 | PLA2G2A (0.39) | PLA2G2AKMT2AICMTPPARGPPARD | |
| SCHEMBL5807179 | 0.83 | KMT2A (0.33) | PLA2G2AKMT2A | |
| SCHEMBL6598794 | 0.82 | PLA2G2A (0.47) | PLA2G2AICMTPPARGPPARDPPARA | |
| SCHEMBL6601718 | 0.82 | PLA2G2A (0.38) | PLA2G2AKMT2AICMTPPARGPPARD | |
| SCHEMBL5812355 | 0.82 | PLA2G2A (0.39) | PLA2G2AKMT2AICMTPPARGPPARD | |
| SCHEMBL6597512 | 0.81 | PLA2G2A (0.37) | PLA2G2AICMTPPARGPPARDPPARA | |
| Acetic Acid SCHEMBL6598580 | 0.81 | S1PR1 (0.40) | PLA2G2AICMTPPARGPPARDPPARA | |
| SCHEMBL5808083 | 0.81 | LTB4R (0.34) | PLA2G2AKMT2AHDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006046683-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AS LEUKOTRIENE AND PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2006-05-04 | — | — | WO | disclosed |