Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 2/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808404 | 0.82 | ALDH1A1 (0.61) | ALDH1A1GAAPOLBHPGDTP53 | |
| SCHEMBL1076744 | 0.72 | ATM (0.65) | ALDH1A1GAAPOLBHPGDNPC1 | |
| SCHEMBL5924069 | 0.72 | CALM1 (0.52) | GAAPOLBHPGDMEN1KMT2A | |
| SCHEMBL27794001 | 0.70 | CALM1 (0.51) | ALDH1A1GAAPOLBMEN1TSHR | |
| SCHEMBL1076743 | 0.65 | ALDH1A1 (0.74) | ALDH1A1GAAHPGDLMNAKMT2A | |
| SCHEMBL19390931 | 0.65 | HRH3 (0.54) | ALDH1A1POLBLMNAL3MBTL1MEN1 | |
| SCHEMBL8632096 | 0.64 | ALDH1A1 (0.50) | ALDH1A1GAAPOLBNPC1LMNA | |
| SCHEMBL1190642 | 0.64 | OXTR (0.51) | ALDH1A1GAAL3MBTL1MEN1MAPK1 | |
| SCHEMBL1190859 | 0.64 | OXTR (0.51) | ALDH1A1GAAL3MBTL1MEN1MAPK1 | |
| SCHEMBL1190645 | 0.64 | OXTR (0.51) | ALDH1A1GAAL3MBTL1MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006069096-A1 | SILANOL DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | PHARMACYCLICS, INC. (US) | 2006-06-29 | — | — | WO | disclosed |