Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808402 | 0.82 | ALDH1A1 (0.61) | ALDH1A1GAAPOLBHPGDNPC1 | |
| SCHEMBL1076744 | 0.75 | ATM (0.65) | ALDH1A1GAAPOLBHPGDNPC1 | |
| SCHEMBL8494840 | 0.74 | POLB (0.40) | ALDH1A1GAAPOLBNPC1RAB9A | |
| SCHEMBL20387961 | 0.72 | ALDH1A1 (0.78) | ALDH1A1GAAPOLBHPGDLMNA | |
| SCHEMBL8492330 | 0.71 | KDM4E (0.52) | ALDH1A1POLBHPGDRAB9ALMNA | |
| SCHEMBL27794001 | 0.70 | CALM1 (0.51) | ALDH1A1GAAPOLBMAPK1MEN1 | |
| SCHEMBL20229497 | 0.69 | CHRM2 (0.56) | ALDH1A1MEN1ALOX15KMT2AHTT | |
| SCHEMBL8493593 | 0.67 | GAA (0.44) | GAATP53L3MBTL1MEN1KMT2A | |
| SCHEMBL18636128 | 0.67 | HDAC1 (0.51) | ALDH1A1POLBHPGDNPC1RAB9A | |
| SCHEMBL11171571 | 0.66 | LMNA (0.42) | ALDH1A1POLBLMNAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006069096-A1 | SILANOL DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | PHARMACYCLICS, INC. (US) | 2006-06-29 | — | — | WO | disclosed |