Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | CA12 | O43570 | 2/20 | 0.66 |
| ▸ | CA9 | Q16790 | 2/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12994640 | 0.90 | MTOR (0.70) | MTORALDH1A1NPSR1CA12CA9 | |
| SCHEMBL29140936 | 0.90 | MTOR (0.78) | MTORALDH1A1NPSR1CA12CA9 | |
| SCHEMBL11168593 | 0.89 | MTOR (0.71) | MTORALDH1A1NPSR1CA12CA9 | |
| SCHEMBL6984082 | 0.89 | MTOR (0.68) | MTORALDH1A1NPSR1CA12CA9 | |
| SCHEMBL29140953 | 0.86 | MTOR (0.65) | MTORALDH1A1ABCC1RAB9ANPY5R | |
| SCHEMBL29140925 | 0.83 | MTOR (0.61) | MTORCA12CA9CA1CA2 | |
| SCHEMBL29140944 | 0.83 | NPY5R (0.78) | MTORALDH1A1NPSR1CA12CA9 | |
| SCHEMBL8174295 | 0.83 | ALDH1A1 (0.65) | MTORALDH1A1NPSR1CA12CA9 | |
| SCHEMBL11419570 | 0.83 | BCHE (0.60) | MTORALDH1A1NPSR1CA12CA9 | |
| SCHEMBL20379674 | 0.82 | SMN1; SMN2 (0.64) | MTORALDH1A1NPC1RAB9ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117383994-A | Preparation method of asymmetric urea compound and asymmetric urea compound | 内蒙古工业大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-110878070-B | Method for preparing asymmetric urea compound | 中国科学院化学研究所 | 2021-08-31 | — | — | CN | disclosed |
| CN-110878070-A | Method for preparing asymmetric urea compound | 中国科学院化学研究所 | 2020-03-13 | — | — | CN | disclosed |
| US-20090111801-A1 | SUBSTITUTED PYRAZINONE DERIVATIVES FOR USE AS A MEDICINE | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-30 | — | — | US | disclosed |
| US-20090111801-A1 | SUBSTITUTED PYRAZINONE DERIVATIVES FOR USE AS A MEDICINE | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-30 | — | — | US | disclosed |
| WO-2007122173-A1 | SUBSTITUTED PYRAZINONE DERIVATIVES FOR USE AS A MEDICINE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-01 | — | — | WO | disclosed |
| WO-2006130426-A2 | MODULATORS OF CCR-5 ACTIVITY | KEMIA, INC. (US) | 2006-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111801-A1 | SUBSTITUTED PYRAZINONE DERIVATIVES FOR USE AS A MEDICINE | ADRA2C, ADRB2, CHRNA5 | MTOR 1627/4885ALDH1A1 710/4885NPSR1 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.