Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28935819 | 0.74 | GRM6 (0.39) | SIGMAR1 | |
| SCHEMBL14034171 | 0.72 | NPY1R (0.39) | OPRM1SIGMAR1TMEM97 | |
| SCHEMBL27618588 | 0.69 | OPRM1 (0.43) | OPRM1SIGMAR1TMEM97 | |
| SCHEMBL24926340 | 0.69 | ACHE (0.45) | — | |
| SCHEMBL12410196 | 0.69 | ACHE (0.45) | — | |
| SCHEMBL3424277 | 0.69 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL14663972 | 0.68 | ALDH1A1 (0.45) | — | |
| SCHEMBL14034000 | 0.65 | PARP1 (0.39) | SIGMAR1 | |
| SCHEMBL6045741 | 0.65 | SMN1; SMN2 (0.55) | OPRM1SIGMAR1TMEM97 | |
| SCHEMBL29330463 | 0.63 | TP53 (0.41) | OPRM1SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006086609-A2 | INHIBITORS OF TRYPTASE | AXYS PHARMACEUTICALS, INC. (US) | 2006-08-17 | — | — | WO | disclosed |