Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394704 | 0.85 | ALDH1A1 (0.53) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL17207241 | 0.84 | CTSA (0.36) | GAAMGAMSIMGAM2FGFR1 | |
| SCHEMBL20377717 | 0.82 | ALDH1A1 (0.46) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL9700721 | 0.80 | FGFR1 (0.41) | GAAMGAMSIMGAM2FGFR1 | |
| SCHEMBL16163330 | 0.80 | MGAM (0.42) | GAAMGAMSIMGAM2FGFR1 | |
| SCHEMBL24288007 | 0.80 | JAK1 (0.32) | SMN1; SMN2RAB9ATDP1MAPT | |
| SCHEMBL20150091 | 0.80 | TP53 (0.32) | KDM4ESMN1; SMN2RAB9AALDH1A1TDP1 | |
| SCHEMBL20230856 | 0.80 | P2RX7 (0.33) | FGFR1FGFR2KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL3657985 | 0.78 | STIM1 (0.49) | KDM4ESMN1; SMN2RAB9AALDH1A1TP53 | |
| SCHEMBL15698575 | 0.77 | ALDH1A1 (0.40) | GAAMGAMSIMGAM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211739-A1 | Use of selective P2X7 receptor antagonists | ABBOTT LABORATORIES | 2006-09-21 | — | — | US | disclosed |
| WO-2006086229-A1 | THE USE OF SELECTIVE P2X7 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2006-08-17 | — | — | WO | disclosed |
| US-6143434-A | HIGH LUMINANCE AND A HIGH LUMINESCENT EFFICIENCY AT A LOW DRIVING VOLTAGE AND HAS EXCELLENT STABILITY IN REPETITIONS OF USE | FUJI PHOTO FILM CO., LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0314104-B1 | SILVER HALIDE PHOTOGRAPHIC MATERIALS | FUJI PHOTO FILM CO., LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-5093222-A | Contrast, negatives | FUJI PHOTO FILM CO., LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0314104-A2 | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-03 | — | — | EP | disclosed |
| US-4740455-A | Heat developable light-sensitive material containing polymethine | FUJI PHOTO FILM CO., LTD. (JP) | 1988-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211739-A1 | Use of selective P2X7 receptor antagonists | P2RX1, P2RX3, P2RX7 | GAA 4313/4885MGAM 4749/4885SI 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.