Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 2/20 | 0.57 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.57 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.57 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.57 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.57 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 10/20 | 0.49 |
| ▸ | HTR1B | P28222 | 5/20 | 0.49 |
| ▸ | DRD3 | P35462 | 5/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | HTR1D | P28221 | 4/20 | 0.49 |
| ▸ | HTR6 | P50406 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | HTR5A | P47898 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5805423 | 0.96 | HTR7 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5808164 | 0.89 | PSEN1 (0.56) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5808140 | 0.82 | HTR7 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8051885 | 0.82 | BDKRB1 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5809435 | 0.79 | HTR7 (0.78) | HTR7HTR1BDRD3HTR1ADRD2 | |
| SCHEMBL5805783 | 0.79 | LMNA (0.55) | MEN1ALDH1A1KMT2AHTR7HTR1B | |
| Bromide SCHEMBL5821556 | 0.77 | HTR7 (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL22633439 | 0.76 | PSEN1 (0.58) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4538143 | 0.75 | RAB9A (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4542142 | 0.74 | HTR7 (0.46) | HTR7HTR1BDRD3HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101828-A1 | INSECTICIDAL ALKYLAMINO PHENYL SULFONAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2006-09-28 | — | — | WO | disclosed |