Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CCR4 | P51679 | 4/20 | 0.39 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5806654 | 0.85 | MPO (0.42) | CYP1A2CYP2C9CYP2C19CYP3A4IDO1 | |
| SCHEMBL5808896 | 0.82 | HTR6 (0.50) | CYP1A2CYP2C9CYP2C19CYP3A4L3MBTL1 | |
| SCHEMBL5809894 | 0.81 | HTR6 (0.54) | CYP1A2CYP2C9CYP2C19CYP3A4KDM4E | |
| SCHEMBL5808997 | 0.79 | NPC1 (0.43) | CYP1A2CYP2C9CYP2C19CYP3A4IDO1 | |
| SCHEMBL5810147 | 0.79 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19CYP3A4L3MBTL1 | |
| SCHEMBL3584464 | 0.78 | GAA (0.46) | CYP1A2CYP2C9CYP2C19CYP3A4IDO1 | |
| SCHEMBL5807474 | 0.78 | CYP1A2 (0.41) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL2768320 | 0.77 | INPPL1 (0.43) | IDO1SLC26A4POLBMAPTINPPL1 | |
| SCHEMBL5810951 | 0.77 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19CYP3A4SLC26A4 | |
| Hydrochloric Acid SCHEMBL2769962 | 0.76 | INPPL1 (0.43) | CYP1A2CYP2C19CYP3A4IDO1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |