Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810951 | 0.84 | CYP1A2 (0.48) | CYP1A2CYP3A4CYP2C9CYP2C19AHR | |
| SCHEMBL5811668 | 0.81 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19AHR | |
| SCHEMBL5808715 | 0.80 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C9CYP2C19AHR | |
| SCHEMBL5810105 | 0.80 | LMNA (0.51) | CYP1A2CYP3A4CYP2C9CYP2C19AHR | |
| SCHEMBL5810331 | 0.78 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL5806654 | 0.77 | MPO (0.42) | CYP1A2CYP3A4CYP2C9CYP2C19AHR | |
| SCHEMBL5809081 | 0.77 | MPO (0.42) | CYP1A2CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL5806020 | 0.77 | IDO1 (0.45) | CYP1A2CYP3A4KDM4EMAPTRAB9A | |
| SCHEMBL5809111 | 0.76 | CNR2 (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19AHR | |
| SCHEMBL5811682 | 0.76 | MAOA (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |