Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | GAPDH | P04406 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213111 | 0.81 | MAPT (0.55) | MAPTSMN1; SMN2ALDH1A1BACE1GAPDH | |
| SCHEMBL14566869 | 0.81 | GAPDH (0.58) | MAPTSMN1; SMN2ALDH1A1S100A4BACE1 | |
| SCHEMBL637237 | 0.80 | S100A4 (0.63) | MAPTSMN1; SMN2ALDH1A1S100A4BACE1 | |
| SCHEMBL30661169 | 0.80 | S100A4 (0.63) | MAPTSMN1; SMN2ALDH1A1S100A4BACE1 | |
| SCHEMBL10377985 | 0.78 | LMNA (0.47) | MAPTSMN1; SMN2ALDH1A1BACE1GAPDH | |
| SCHEMBL22336250 | 0.78 | MAPT (0.55) | MAPTSMN1; SMN2ALDH1A1BACE1POLB | |
| SCHEMBL27989381 | 0.78 | PTPN1 (0.59) | MAPTSMN1; SMN2ALDH1A1BACE1POLB | |
| SCHEMBL15085173 | 0.77 | MAPT (0.62) | MAPTSMN1; SMN2ALDH1A1BACE1POLB | |
| SCHEMBL4642778 | 0.76 | MAPT (0.61) | MAPTSMN1; SMN2ALDH1A1S100A4BACE1 | |
| SCHEMBL30003084 | 0.73 | IDO1 (0.62) | MAPTALDH1A1GAPDHCA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006107827-A1 | SKIN BONDING PROCESS | CREIGHTON UNIVERSITY (US) | 2006-10-12 | — | — | WO | disclosed |