Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.63 |
| ▸ | CDC25B | P30305 | 5/20 | 0.62 |
| ▸ | CDC25A | P30304 | 4/20 | 0.62 |
| ▸ | IDO1 | P14902 | 2/20 | 0.62 |
| ▸ | GAPDH | P04406 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30661169 | 1.00 | S100A4 (0.63) | S100A4CDC25BCDC25AIDO1GAPDH | |
| Dodecane SCHEMBL11580698 | 0.89 | S100A4 (0.53) | S100A4CDC25BCDC25AIDO1GAPDH | |
| SCHEMBL14439324 | 0.86 | PTPN1 (0.62) | S100A4CDC25BCDC25AIDO1PTPN1 | |
| SCHEMBL14566869 | 0.83 | GAPDH (0.58) | S100A4CDC25BCDC25AIDO1GAPDH | |
| SCHEMBL16300544 | 0.83 | S100A4 (0.60) | S100A4CDC25BCDC25AIDO1GAPDH | |
| SCHEMBL5810487 | 0.80 | MAPT (0.44) | S100A4CDC25BCDC25AIDO1GAPDH | |
| SCHEMBL30749477 | 0.79 | S100A4 (0.78) | S100A4CDC25BCDC25AIDO1GAPDH | |
| SCHEMBL8142691 | 0.79 | S100A4 (0.78) | S100A4CDC25BCDC25AIDO1GAPDH | |
| SCHEMBL5816985 | 0.79 | ALDH1A1 (0.52) | S100A4CDC25BCDC25AIDO1GAPDH | |
| SCHEMBL5822269 | 0.79 | KDM4E (0.52) | S100A4CDC25BCDC25AIDO1GAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174589-A1 | PHOTOREDOX RADICAL BENZYLATION PROCESS | CENTRE NAT RECH SCIENT (FR) | 2024-05-30 | — | — | US | disclosed |
| CN-117142938-A | Method for preparing 1, 4-naphthoquinone compound by selectively oxidizing aromatic ketone | 大连理工大学 | 2023-12-01 | — | — | CN | disclosed |
| EP-4053096-A1 | PHOTOREDOX RADICAL BENZYLATION PROCESS | Centre national de la recherche scientifique (FR) | 2022-09-07 | — | — | EP | disclosed |
| EP-2152657-B1 | PROCESS FOR THE PREPARATION OFTRANS-2,3-DISUBSTITUTED NAPHTHOQUINONES | LABORATORIO CHIMICO INT SPA (IT) | 2012-02-22 | — | — | EP | disclosed |
| US-7842840-B2 | Process for the preparation of trans-2,3-disubstituted naphthoquinones | LABORATORIO CHIMICO INTERNAZIONALE, S.P.A. (IT) | 2010-11-30 | — | — | US | disclosed |
| CN-101844982-A | Preparation method of 2-acetoxyl-1,4-naphthoquinone | UNIV TIANJIN POLYTECHNIC | 2010-09-29 | — | — | CN | disclosed |
| CN-101844982-A | Preparation method of 2-acetoxyl-1,4-naphthoquinone | UNIV TIANJIN POLYTECHNIC | 2010-09-29 | — | — | CN | disclosed |
| US-20100137644-A1 | Process for the preparation of trans-2,3-disubstituted naphthoquinones | LABORATORIO CHIMICO INTERNAZIONALE, S.P.A. (IT) | 2010-06-03 | — | — | US | disclosed |
| EP-2152657-A1 | PROCESS FOR THE PREPARATION OFTRANS-2,3-DISUBSTITUTED NAPHTHOQUINONES | Laboratorio Chimico Internazionale S.p.A. (IT) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008139290-A1 | PROCESS FOR THE PREPARATION OFTRANS-2,3-DISUBSTITUTED NAPHTHOQUINONES | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2008-11-20 | — | — | WO | disclosed |
| US-6043286-A | COMBATTING WHITE FLY OR LEPIDOPTERA PESTS | BTG INTERNATIONAL LIMITED (GB) | 2000-03-28 | — | — | US | disclosed |
| US-5962002-A | 1,1,4,4-SUBSTITUTED DIHYDRONAPHTHALENE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 1999-10-05 | — | — | US | disclosed |
| EP-0802730-B1 | PESTICIDAL COMPOUNDS | BTG INT LTD (GB) | 1999-06-23 | — | — | EP | disclosed |
| EP-0802729-A1 | PESTICIDAL COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 1997-10-29 | — | — | EP | disclosed |
| EP-0802730-A1 | PESTICIDAL COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021355-A1 | PESTICIDAL COMPOUNDS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-07-18 | — | — | WO | disclosed |
| WO-1996021354-A1 | PESTICIDAL COMPOUNDS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137644-A1 | Process for the preparation of trans-2,3-disubstituted naphthoquinones | NQO1, POLQ, SQLE | S100A4 4673/4885CDC25B 235/4885CDC25A 400/4885 |
| US-20240174589-A1 | PHOTOREDOX RADICAL BENZYLATION PROCESS | H1-2, H1-3, H1-0 | S100A4 2534/4885CDC25B 3693/4885CDC25A 4174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.