Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678934 | 0.73 | CECR2 (0.38) | IDH1 | |
| SCHEMBL5777245 | 0.72 | BRD4 (0.34) | ALDH1A1RORC | |
| SCHEMBL5774211 | 0.71 | KMO (0.36) | TSHRKMT2A | |
| SCHEMBL9480085 | 0.71 | TSHR (0.36) | TSHRHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL8878642 | 0.69 | TSHR (0.41) | TSHRHTTMEN1KMT2ANPSR1 | |
| SCHEMBL25359627 | 0.69 | TSHR (0.41) | TSHRHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL25354585 | 0.69 | TSHR (0.41) | TSHRHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL5775170 | 0.68 | COMT (0.36) | MEN1KMT2AALDH1A1IDH1 | |
| SCHEMBL16063484 | 0.67 | TSHR (0.33) | TSHRHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL16063459 | 0.67 | TSHR (0.33) | TSHRHTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885885-B1 | PYRIDONE DERIVATIVES AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2006-01-04 | — | — | EP | disclosed |
| US-6472348-B1 | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-10-29 | — | — | US | disclosed |
| US-6265349-B1 | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6048823-A | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0885885-A1 | PYRIDONE DERIVATIVES AND HERBICIDES | KumaiI Chemical Industry Co., Ltd. (JP) | 1998-12-23 | — | — | EP | disclosed |